
Proteins distinguish the A and B blood-group antigens. Subtle differences in the terminal residues of the sugars attached to these surface The ABO blood-group antigens, for example, are glycoproteins expressed In the latter case, the antibody’s affinity for the cross-reactingĮpitope is usually less than that for the original epitope.Ĭross-reactivity is often observed among polysaccharide antigens that contain similar Such cross-reactivity occurs if two different antigens share an Nederlânsk - Frysk (Visser W.)Īlthough Ag-Ab reactions are highly specific, in some cases antibody elicited by one antigen canĬross-react with an unrelated antigen.
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